Is there a treatment(s) for Turcot syndrome?
The treatment of Turcot syndrome is directed toward the specific symptoms that are apparent in each individual. Treatment starts with screening for colon cancer. This involves having a colonoscopy on a regular basis. The frequency and starting age depends on the gene mutation. People with an APC gene mutation will likely start colonoscopies around the age of 10 and have one every one to two years. People with a MLH1 or PMS2 gene mutation will likely start colonoscopies in their early 20s, and have one every one to two years. If polyps are found, then a person might have surgery to remove the colon, or part of the colon. This is called a colectomy.
Individuals with Turcot syndrome can also consider periodic neurological screenings to test for the presence of a brain tumor. There are no specific guidelines for the frequency and method of screening for brain cancer. Individuals from families diagnosed with Turcot syndrome are encouraged to talk with a neurologist, a doctor who specializes in problems with the brain and central nervous system, about screening options.Treatment for brain tumors depends upon the type, size, and location of the tumor. It may include surgery to remove as much of the tumor as is possible without causing damage to the surrounding tissue. Surgery is often followed or accompanied by radiation and/or chemotherapy treatments.
SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/turcot-syndrome/treatment/4812 • DATE UPDATED: 2016-06-25