What does having an extra chromosome in Trisomy 13 cause?
Chromosomes are made up of genes, and genes act as instructions for the body. Extra or missing genetic information can lead to health problems, because there are altered instructions for the cells of the body. Adding an extra, complete copy of chromosome 13 can cause heart defects, intellectual disability, birth defects of the brain and face, growth problems and other health problems.
Curr Opin Pediatr. 2012 Dec;24(6):672-8. doi: 10.1097/MOP.0b013e3283595031.Perspectives on the care and management of infants with trisomy 18 and trisomy 13: striving for balance.Carey JC1