What is SYNGAP1?

SYNGAP1 is a genetic cause of intellectual disability (moderate to severe), seizures, and autism. People living with SYNGAP1 may also have issues with mood disorders, impulsive behavior, and attention deficits. They tend to have these neurological issues without also having birth defects (non-syndromic intellectual disabilty). SYNGAP1 is caused by changes or mutations in the SYNGAP1 gene. Most often the SYNGAP1 gene changes in an person living with SYNGAP1 happened for the first time in that person and are not passed down from a parent.

A genetic professional such as a medical geneticist and/or genetic counselor can provide more information about SYNGAP1, testing, and treatment options. To find a genetic counselor in an specific area, use the NSGC find a genetic counselor webpage.

Excellent information on SYNGAP1 can also be found on the NORD rare disease entry on NORD SYNGAP1 webpage as well as the main SYNGAP1 support group website: Bridge the Gap: Syngap Educational and Research Foundation.

Show More Content Like This

More Overview Content

What is another name for SYNGAP1?

What is another name for SYNGAP1?

Other names for SYNGAP1 include:

  • SYNGAP1-related intellectual disability
  • mental retardation, autosomal dominant 5
  • MRD5

We use cookies to ensure that we give you the best experience on our website. By continuing to browse this site, you are agreeing to our use of cookies.

Continue Find out more about our use of cookies and similar technology

This content comes from a hidden element on this page.

The inline option preserves bound JavaScript events and changes, and it puts the content back where it came from when it is closed.

Remember Me