Primary Distal Renal Tubular Acidosis


Are there any forms of primary distal renal tubular acidosis that include anemia as a symptom?

When an individual has two mutations in the SLC4A1 gene, it can cause primary distal renal tubular acidosis (primary dRTA) and low blood iron caused by abnormal red cell shape and lifespan (hemolytic anemia). In Southeast Asian countries like Thailand, Malaysia, the Philippines, Papua New Guinea, and Laos, there is an increased incidence of having both primary dRTA and hemolytic anemia together caused by having two nonworking copies of the SLC4A1 gene.

Park, E., Phaymany, V., Yi, E. S., Phangmanixay, S., Cheong, H. I., & Choi, Y. (2018). Primary Autosomal Recessive Distal Renal Tubular Acidosis Caused by a Common Homozygous SLC4A1 Mutation in Two Lao Families. Journal of Korean medical science, 33(13), e95. doi:10.3346/jkms.2018.33.e95

This content comes from a hidden element on this page.

The inline option preserves bound JavaScript events and changes, and it puts the content back where it came from when it is closed.

Remember Me