What is a paraganglioma?
Paragangliomas are noncancerous tumors of the peripheral nervous system (the nerves that are not part of the brain and spinal cord). They can occur in any nerve and often near a major artery. The most common site paragangliomas develop is in the abdomen where approximately 85-90% are located. Sometimes paragangliomas release hormones like noradrenaline or adrenaline that cause a high blood pressure, hot flashes, racing heartbeat, and headaches, other times they do not. Most of the time paragangliomas occur as sporadic tumors, that is, they are not inherited. Paragangliomas may also be surgically removed if they are secreting hormones, causing a health problem such making it difficult to breathe, or have become cancerous. Paragangliomas can occur as a isolated finding or part of a genetic conditions such as multiple endocrine neoplasia (MEN) type 2, von Hippel-Lindau syndrome, or Neurofibromatosis type 1.
SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/paragangliomas-109959/overview/68981 • DATE UPDATED: 2019-11-28
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