How is otosclerosis inherited?
Everyone typically has two copies of every gene in their body, one inherited from their mother, and the other inherited from their father. There are multiple ways otosclerosis is inherited. Otoscelerosis is usually inherited in a “multifactorial” manner. This means that the genes predisposing to otosclerosis are not enough to cause the condition alone, and multiple other factors (like hormones and viral infections) are also needed. Otosclerosis can also be inherited in an “autosomal dominant” manner. This means that only a change/mutation in only one copy of a gene that causes otosclerosis is enough to cause the condition.
SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/otosclerosis/inheritance/9161 • DATE UPDATED: 2016-06-15
Otosclerosis. American Hearing Research Foundation. (http://american-hearing.org/disorders/otosclerosis/)