Mucopolysaccharidosis Type VI
If this is a predisposition gene, what the chances I will get Mucopolysaccharidosis Type VI?
Having genetic changes in the ARSB gene associated with mucopolysaccharidosis type VI (MPS VI) is not a predisposition, but a cause of MPS VI. We all have two copies of ARSB in each of our cells and both of these copies need to have changes in order for someone to have MPS VI. If an individual only has changes in one copy, then they are called a carrier and do not have any symptoms. No other conditions are associated with changes in the ARSB gene.
Genetics Home Reference - https://ghr.nlm.nih.gov/condition/mucopolysaccharidosis-type-vi