What are the main symptoms of Lynch syndrome?
The main symptom or feature of Lynch syndrome is an increased risk to develop cancer. In general, people with Lynch syndrome have an increased risk to develop colorectal (colon/rectal), uterine (endometrial), ovarian, and stomach cancer. Cancers of the small intestine, urinary tract, brain/central nervous system, liver, biliary tract, and pancreas are also associated with Lynch syndrome. Sebaceous neoplasms, or small growths on the skin, may also be seen with Lynch syndrome. These skins findings can be either benign (non-cancerous) or malignant (cancerous).
SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/lynch-syndrome-i/symptoms/2191 • DATE UPDATED: 2020-01-09
Kohlmann W, Gruber SB. Lynch Syndrome. 2004 Feb 5 [Updated 2018 Apr 12]. In: Adam MP, Ardinger HH, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1211/
Lynch syndrome. [Internet]. Genetics Home Reference. [Reviewed January 2020]. Available from: http://ghr.nlm.nih.gov/condition/lynch-syndrome