Lynch syndrome

Overview

What is Lynch syndrome?

Lynch syndrome is a cancer condition caused by genetic changes in the MLH1, MSH2, MSH6, PMS2, or EPCAM genes. Genetic changes in these genes can be passed from parent to child. In other words, Lynch syndrome runs in families. Lynch syndrome is the most common cause of hereditary colon cancer. People with a genetic change in a gene associated with Lynch syndrome have an increased risk for certain types of cancer, including colorectal, uterine, ovarian, and stomach cancers. Both men and women can have Lynch syndrome.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/lynch-syndrome-i/overview/2185 • DATE UPDATED: 2016-07-16

References

http://ghr.nlm.nih.gov/condition/lynch-syndrome

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