Li-fraumeni syndrome 1

Overview

What is Li-Fraumeni syndrome?

Li-Fraumeni syndrome is a cancer condition caused by genetic changes in the TP53 gene. Genetic changes in this gene can be passed from parent to child. In other words, Li-Fraumeni syndrome runs in families. People with a genetic change in TP53 have an increased risk for certain types of cancer, including breast cancer, soft tissue sarcoma, osteosarcoma, and other cancers. Both men and women can have Li-Fraumeni syndrome.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/li-fraumeni-syndrome-1/overview/2269 • DATE UPDATED: 2016-06-06

References

http://ghr.nlm.nih.gov/condition/li-fraumeni-syndrome

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