Hereditary Diffuse Gastric Cancer

Treatment

Is there a treatment(s) for hereditary diffuse gastric cancer?

There is no specific treatment to prevent diffuse gastric cancer syndrome. However, there are ways to manage and screen for gastric, breast, and colon cancer to try and prevent or discover cancer at an earlier stage.

References
  • Schneider, K. (2013). Counseling about Cancer: Strategies for Genetic Counseling. 3rd Ed.
Show More Content Like This

More Treatment Content

Are there other organ or symptom specific treatments for hereditary diffuse gastric cancer?

Are there other organ or symptom specific treatments for hereditary diffuse gastric cancer?

There is no specific treatment to prevent diffuse gastric cancer syndrome. However, there are ways to manage and screen for gastric, breast, and colon cancer to try and prevent or discover cancer at an earlier stage. Hereditary diffuse gastric cancer screening recommendations include:

  • Removing the stomach before cancer diagnosis (prophylactic gastrectomy)- recommended after genetic testing results are known, and at age 20 or 5 years prior to the earliest diagnosis in the family
  • Endoscopic surveillance- only done if gastrectomy is not pursued, and multiple random biopsies will be taken. This should be done annually.
  • Breast cancer screening- monthly self-breast exams, biannual clinical breast exams, annual mammograms, and annual MRI’s beginning at age 35
  • Colon cancer screening- colonoscopies every 3-5 years. Begin these at 40 or 10 years younger than the earliest diagnosis in the family.
References
  • Fitzgerald, R. C., Hardwick, R., Huntsman, D., Carneiro, F., Guilford, P., Blair, V., ... & Caldas, C. (2010). Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research. Journal of medical genetics, 47(7), 436-444.
  • Kluijt, I., Siemerink, E. J., Ausems, M. G., van Os, T. A., de Jong, D., Simões?Correia, J., ... & Hoogerbrugge, N. (2012). CDH1?related hereditary diffuse gastric cancer syndrome: Clinical variations and implications for counseling. International Journal of Cancer, 131(2), 367-376.

We use cookies to ensure that we give you the best experience on our website. By continuing to browse this site, you are agreeing to our use of cookies.

Continue Find out more about our use of cookies and similar technology

This content comes from a hidden element on this page.

The inline option preserves bound JavaScript events and changes, and it puts the content back where it came from when it is closed.

Remember Me