Hemophilia A


What is hemophilia A?

Hemophilia A is a genetic bleeding disorder caused by a change in a gene on the X chromosome called F8. This causes a lack or shortage of the factor VIII (FVIII) protein in their blood that is supposed to help form clots to stop bleeding in response to an injury. People who lack this protein often bleed longer than others and require medicine to stop bleeding. They may have frequent nosebleeds and can have internal bleeding, or bleeding inside their body, without any kind of injury. They also tend to have bleeding in their joints and muscles. People with a severe type of hemophilia A have more bleeding symptoms than people with a mild type. You can read more about the signs and symptoms of hemophilia A here: https://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/signs

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/hemophilia-a/overview/1461 • DATE UPDATED: 2016-06-01


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