Fetal parvovirus syndrome


What is fetal parvovirus syndrome?

Fetal parvovirus syndrome occurs when a baby is infected with a virus called parvovirus B19 before birth. The disease typically doesn't present a problem for pregnant women and their babies, as about half of pregnant women are immune to parvovirus B19. Those pregnant mothers who aren't immune usually experience a mild illness when exposed to fifth disease. Although the maternal symptoms are short-lived, in rare cases, the infection can lead to serious complications in the developing fetus, including severe low levels of iron (anemia) and severe fluid storage (hydrops fetalis), liver disease (hepatitis) and heart issues (inflammation of the heart muscle and cardiac failure). An expectant mother may have a miscarriage as a result of the parvovirus infecting her baby, but this happens less than 5% of the time in all pregnant woman with parvovirus B19 infection.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/fetal-parvovirus-syndrome/overview/665 • DATE UPDATED: 2016-06-16



Lamont RF, Sobel JD, Vaisbuch E, et al; Parvovirus B19 infection in human pregnancy. BJOG. 2011 Jan; 118(2):175-86. doi: 10.1111/j.1471-0528.2010.02749.x. Epub 2010 Oct 13.

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