Familial hypospadias

Overview

What is familial hypospadias?

Familial hypospadias is a common birth defect that affects males, and occurs when the opening of the urethra (the tube that carries urine from the bladder to the outside of the body) is not located at the tip of the penis. Familial means that multiple members of the family are affected by this condition. If hypospadias is not treated early, problems can occur later in life that affect sexual intercourse or cause problems with urinating while standing.

The size and location of the opening of the urethra is different from person to person with hypospadias. Depending on the location of the opening and severity of the hypospadias, the surgical treatment plan and outcome can be different.

References
  • http://ghr.nlm.nih.gov/glossary=hypospadias
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How common is familial hypospadias?

Are there different types of hypospadias?

How common is familial hypospadias?

Hypospadias is the second most common birth defect affecting male genitalia. In the United States, it is estimated that 1 out of every 200 boys is born with hypospadias. However, familial hypospadias, meaning hypospadias that affects multiple members of a family, accounts for only 10% of cases.

References
  • https://clinicaltrials.gov/ct2/show/NCT02495090
  • http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=440
Are there different types of hypospadias?

There are three types of hypospadias, depending on the location of the opening of the urethra (the tube that carries urine from the bladder to the outside of the body). The three types are:

Subcoronal: The opening of the urethra is located near the head of the penis.

Midshaft: The opening of the urethra is located along the shaft of the penis.

Penoscrotal: The opening of the urethra is located where the penis and scrotum meet.

References
  • http://www.cdc.gov/ncbddd/birthdefects/hypospadias.html

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