Kidney and Urinary Diseases

Your kidneys are amazing organs helping to remove waste from blood, balance fluids within our body, form urine, and aid in other important functions of the body. Inherited or genetic causes of kidney diseases are rare, with the exception of autosomal dominant polycystic kidney disease, the fourth most common cause of end-stage renal disease in developed countries.

Advances in genetic techniques assessing the kidney are providing novel insights into kidney diseases, especially diagnosis, classification, pathogenesis and therapy. Many diseases that you are born with (congenital kidney diseases) are due to single gene defects (e.g., some cases of nephrotic syndrome resistant to steroids). It is also becoming clear that some adult-onset kidney diseases - which are far more common- have a genetic component.

Congenital anomalies of the kidney and urinary tract anatomy represent approximately 30% of all prenatally diagnosed malformations.

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