What does it mean if CARASIL seems to run in my family?
Genetic conditions can often appear to "run in a family," if more than one person in the family has the condition. Some disorders that affect multiple family members are caused by gene mutations, which can be inherited (passed from parent to child). Other conditions that appear to "run in families" are not caused by mutations environmental factors or a combination of environmental and genetic factors are responsible.
CARASIL is an autosomal recessive disease, which means both copies of the gene have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene but often do not show signs or symptoms of the condition. Autosomal recessive disorders are typically not seen in every generation of an affected family.