Canavan disease


How common is Canavan disease?

As with many rare disorders, the incidence and prevalence of Canavan disease is not known. The disorder can affect people of any ethnicity, but occurs in people of Eastern European (Ashkenazi) Jewish heritage more frequently, where it is estimated to occur in about 1 in 6,400 to 1 in 13,500 people. The carrier rate in this population is about 1 in 40-82 people. Canavan disease is believed to be far less common in people of other ancestries. In people of other ancestries, it is estimated to affect about 1 in 100,000 people.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • • DATE UPDATED: 2016-06-16


Canavan Disease. Genetic Home Reference website. Retrieved April 29, 2016, from

Matalon R, Michals-Matalon K. Canavan Disease. In: Rosenberg RN, Pascual JM, eds. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. 5th edition. Philadelphia, PA:Elsevier, Inc.;2015.

Matalon R, Michals-Matalon K. GeneReviews website. Updated August 11, 2011. Retrieved April 29, 2016, from

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