Canavan disease

Causes

Do changes in the ASPA gene lead to a predisposition to Canavan disease or do they cause Canavan disease?

Unexpected changes in the ASPA gene cause Canavan disease. Doctors are not aware of any other factors required for the development of the disorder.

Matalon R, Michals-Matalon K. GeneReviews website. Updated August 11, 2011. Retrieved April 29, 2016, from http://www.ncbi.nlm.nih.gov/books/NBK1234/

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