BRCA1, familial breast-ovarian cancer susceptibility 1

Treatment

What can be done to reduce the risk for ovarian cancer for people with a BRCA1 gene mutation?

Unfortunately, there are not good screening methods for ovarian cancer. For women, a prophylactic salpingo-oophorectomy (removal of the ovaries and fallopian tubes), can reduce the risk of ovarian cancer by 96%. This is why healthcare providers will more strongly recommend consideration of a bilateral salpingo- oophorectomy for women around 35-40 years of age who are done having children, or 40-45 years of age for women who have had a bilateral mastectomy. Healthcare providers may also recommend using medication, like birth control pills, to reduce ovarian cancer risk.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/brca1-familial-breast-ovarian-cancer-susceptibility-1/treatment/7065 • DATE UPDATED: 2019-07-09

References

http://www.ncbi.nlm.nih.gov/books/NBK1247/

National Comprehensive Cancer Network. Genetic/Familial High-Risk Assessment: Breast and Ovarian (Version 2.2016). https://www.nccn.org/professionals/physician_gls/pdf/genetics_screening.pdf.

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