BRCA1, familial breast-ovarian cancer susceptibility 1


What can be done to reduce the risk for ovarian cancer for people with a BRCA1 gene mutation?

Unfortunately, there are not good screening methods for ovarian cancer. For women, a prophylactic salpingo-oophorectomy (removal of the ovaries and fallopian tubes), can reduce the risk of ovarian cancer by 96%. This is why healthcare providers will more strongly recommend consideration of a bilateral salpingo- oophorectomy for women around 35-40 years of age who are done having children, or 40-45 years of age for women who have had a bilateral mastectomy. Healthcare providers may also recommend using medication, like birth control pills, to reduce ovarian cancer risk.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • • DATE UPDATED: 2019-07-09


National Comprehensive Cancer Network. Genetic/Familial High-Risk Assessment: Breast and Ovarian (Version 2.2016).

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