BRCA1, familial breast-ovarian cancer susceptibility 1
Is prenatal testing available for Hereditary Breast and Ovarian Cancer syndrome and the BRCA1 gene mutation?
Preimplantation genetic diagnosis (PGD) is available for Hereditary Breast and Ovarian Cancer syndrome if one of the parents is known to carry a BRCA1 mutation. PGD is performed on embryos produced through IVF. PGD allows for parents to only implant embryos into the mother's uterus that do not have the BRCA1 gene mutation. PGD is still a very costly procedure though, and it is not guaranteed to lead to pregnancy every time.
Some labs may accept prenatal specimens for genetic testing if a parent is known to carry a BRCA1 mutation. With prenatal testing, the baby's DNA is tested during the pregnancy to determine whether the baby has the BRCA1 gene mutation. The procedures available to obtain the baby's DNA during a pregnancy are associated with a risk of pregnancy loss. Prenatal testing is not commonly utilized or recommended for adult onset conditions like Hereditary Breast and Ovarian Cancer syndrome.