Is Antley-Bixler syndrome considered a disorder of steroidogenesis?
When Antley-Bixler syndrome is caused by changes to the POR gene it is considered a disorder of steroidogenesis. Changes to the POR gene decreases activity of the cytochrome P450 oxidoreductase leading to the disruption of steroid hormone production.
Cytochrome P450 oxidoreductase deficiency - Genetics Home Reference - NIH. (n.d.). Retrieved December 25, 2018, from https://ghr.nlm.nih.gov/condition/cytochrome-p450-oxidoreductase-deficiency#statistics