ankylosing spondylitis

Overview

What is ankylosing spondylitis?

Ankylosing spondylitis, or AS, is a chronic inflammatory disease and a type of arthritis that primarily affects the spine. "Ankylosing" in medical terms means "fusing together". "Spondylo" is derived from the Greek word for "vertebra" and the ending, "itis" means inflammation, in the case of AS, of the spinal vertebrae. AS can cause inflammation between the vertebrae (the bones that make up your spine), and in the joints between the spine and hips. In some people, it may cause some of your vertebrae to fuse together, or affect other joints. AS is part of a larger grouping of arthritis-associated diseases called spondyloarthritis (SpA). The hallmark feature found in AS is the involvement of the sacroiliac (SI) joints. AS can also cause pain, stiffness and inflammation in other body areas like the shoulders, hips, ribs and small bones of the hands and feet. Ankylosing spondylitis can also affect other areas of the body like the eyes (iritis), and rarely the heart and the lungs.

SOURCE: Emory University - Department of Human Genetics in collaboration with ThinkGenetic • https://www.thinkgenetic.com/diseases/ankylosing-spondylitis-2588/overview/6997 • DATE UPDATED: 2016-06-21

References

"Ankylosing Spondylitis: MedlinePlus." U.S National Library of Medicine. U.S. National Library of Medicine, 22 Oct. 2015. Web. 20 Dec. 2015.

Ankylosing Spondylitis: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact a ThinkGenetic Counselor

Do you have additional questions that haven't been answered? Ask a ThinkGenetic Counselor — a real expert in the field of genetics. Just fill out this form to send an email. We will be in touch within 48 hours.

Please sign me up for your mailing list.

This content comes from a hidden element on this page.

The inline option preserves bound JavaScript events and changes, and it puts the content back where it came from when it is closed.

Remember Me

Welcome to the ThinkGenetic beta. More content is added weekly so come back and check often. Please provide your feedback by filling out a contact us form.