Amyotrophic lateral sclerosis 1
Is there a genetic predisposition or cause of amyotrophic lateral sclerosis?
There are two types of amyotrophic lateral sclerosis (ALS): acquired and familial. People who have familial ALS develop the disease because they have inherited genetic changes that cause the disease. About 5-10% of ALS is familial. Most people who have ALS have the acquired type, meaning that it does not seem to be caused by a single genetic change and may be the result of environmental and other factors.