What happens if I get a liver transplant to treat alpha-1 antitrypsin deficiency?
If you receive a liver transplant from a donor without alpha-1 antitrypsin deficiency (AATD), your new liver will make normal levels of alpha-1 antitrypsin (AAT) protein. This means that the level of AAT in your body should no longer be low. A liver transplant will not reverse any lung damage that has already occurred. If a living donor, such as a family member, is your donor, it is important to test them for AATD before the donation happens. Although a liver transplant cures a person's low AAT levels, a liver transplant is a serious surgery that requires medications for life to combat rejection. Liver transplantation is a last treatment option for people who need it.