Acute intermittent porphyria
How will I know if I need a liver transplant for my acute intermittent porphyria?
You and your doctor can work together to decide the best path to treat your acute intermittent porphyria (AIP). Usually, patients who need liver transplants are those that are having a life-threatening attack, don't respond to medicines, or have a poor quality of life because of the disease. This is mostly a last resort treatment.
Acute Intermittent Porphyria. Gene Reviews. (http://www.ncbi.nlm.nih.gov/books/NBK1193/)