Achondrogenesis

Achondrogenesis types 1A and 1B are inherited in an autosomal recessive manner. Both parents are unaffected carriers of a genetic change and have a 1 in 4 or 25% chance of having an affected child. Achondrogenesis type 2 is inherited in an autosomal dominant manner and only one copy of the gene needs to be abnormal in order to be affected with the condition. Due to the lethality of achondrogenesis type 2 is it always a new mutation.